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It is not known whether this potentiation of ampicillin rashes is due to allopurinol or the hyperuricemia present in these patients. MetabolicKrasinger and colleagues suggest that it may be reasonable to add allopurinol to the pancreatic enzyme treatment regimen in CF patients that have a urine pH of less than 6 and also excrete large amounts of uric acid. A 63-year-old man receiving allopurinol for gout developed progressive uremia, proteinuria, edema, and purpura after beginning quinidine therapy. Up to 300 milligrams (mg) of allopurinol can be taken at one time. Allopurinol will not relieve a gout attack that has already started.

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